Maria Spies

Associate Professor
Department: 
Department of Biochemistry
College: 
Carver College of Medicine
University: 
The University of Iowa
Phone: 
(319) 335-3221
Office: 
4-532 BSB

Work in the Spies Lab focuses on genome caretakers at the intersection of the 3Rs of DNA maintenance (Replication, Recombination, and DNA Repair). Understanding the molecular bases and regulation of these processes is fundamentally important because accumulation or incomplete repair of DNA lesions can lead to genetic instability and chromosomal rearrangements causing cancer and cell senescence.